Generation Mechanism of Radical Species by Tyrosine-Tyrosinase Reaction
نویسندگان
چکیده
منابع مشابه
Generation Mechanism of Radical Species by Tyrosine-Tyrosinase Reaction
Alleviated melanin formation in the skin through inhibition of tyrosine-tyrosinase reaction is one of the major targets of cosmetics for whitening ability. Since melanin has a pivotal role for photoprotection, there are pros and cons of inhibition of melanin formation. This study applying electron spin resonance (ESR)-spin trapping method revealed that (•)H and (•)OH are generated through tyros...
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* This study was supported by a grant from the National Science Foundation. A preliminary report was given by Dr. Yasunobu at the Conference on Pigment Cell Biology, Houston, Texas, November 1957. t Present address, Department of Chemistry,. University of Hawaii. $ Senior Postdoctoral Fellow of the National Science Foundation at the Department of Chemistry, University of Cambridge. mumto minimu...
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The tyrosine hydroxylase activity of tyrosinase from hamster melanoma has been studied by measurement of the release of tritium from tyrosine-3,5-3H. Experiments with mixtures of tyrosine3 ,5-3H and tyrosine-r4C show that there is little or no tritium rate effect in this reaction. Dopa is the most effective hydrogen donor and will eliminate the lag period when used in catalytic amounts. 2-Amino...
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ژورنال
عنوان ژورنال: Journal of Clinical Biochemistry and Nutrition
سال: 2010
ISSN: 1880-5086,0912-0009
DOI: 10.3164/jcbn.10-48